Find one example of an application (use) of modern biotechnology (requiring the manipulation of DNA)

Find one example of an application (use) of modern biotechnology (requiring the manipulation of DNA)How do I choose my own application?In short, you want to find something that is made using recombinant DNA- so something that is the result of DNA being engineered by humans in a lab. Page 175 of your lab manual has some information on what that means, but I’ve also included a list below for you to choose from or to give you inspiration. However, there are three criteria that you will want to keep in mind while deciding on a topic:1. Be specific. You only have a paragraph, so “Genetically Modified Crops” or “Edible Vaccines” are too big (you can fill textbooks with this information). You need to choose one example, such as Arctic Apples or Hepatitis B Potatoes (those are potatoes that vaccinate from Hep B, not give you Hep B.)2. Focus on an application, not a technique. For example, Gene Drives and CRISPR are both techniques- the tools used to make something, not the final product. I want you to tell me about the product.3. Focus on a topic that is practical, not theoretical. The reason here is simply so that you can find a relevant research paper. If no one has actually made it, you won’t be able to find much useful information.
Below is a list of potential applications that you are welcome to choose from or use as inspiration. The Wikipedia article on Applications of Genetic Engineering (Links to an external site.) also has a number of examples, but be aware that they vary in complexity, and are not all appropriate for this assignment.Genetically Modified Animals ATryn GoatsMice for Laboratory ModelsPigs for XenotransplantationGenetically Modified Crops ApplesBananasCanolaCarrotsChickpeasCorn/MaizePapayaSoybeansTomatoesWheatBioremediation via GM OrganismsCyanobacteria for Biofuel productionEdible Vaccines (choose one)Gene Therapy (choose one)Malaria-resistant MosquitoesVaccines (choose one- must involve recombinant DNA techniques)Note: Topics already covered in the lab manual (i.e. forensic investigations, paternity testing, and Insulin production) as well as the topic used as an example (Golden Rice) are not eligible.
Your description should include:1. A description of the application (what is it?)2. A description of how it is beneficial or useful (why should I care?)3. A brief description of the biotechnology used to make the application (how is this made?)4. You will also need to include at least one reference to a peer-reviewed scientific journal article (see next page for more information on this.)
Your Application should be:An Application. Techniques, such as CRISPR-Cas9, are not applications; they are tools. Your topic should be about the application instead.Practical. Theoretical applications that have not actually been tested or used aren’t appropriate. Focus on things we’re actually doing now.Specific. “GMOs” or “Vaccines” are immensely large topics, and you won’t be able to summarize these in any kind of detail in a single paragraph. Choose a single organism, crop, disease, vaccine, etc. to give specific details about.But how many words?However many it takes to give us the information asked for.The length of your paragraph will depend somewhat on the complexity of the topic you chose- some things are simply easier to explain. In general, scientific writing rewards being concise. Why use three sentences when you could use one?If that makes you uncomfortable, then know that students have been given 100% on this assignment for as few as 4 sentences, and for as much as filling a page.
How formal should my writing be?In general, your writing should be scientific; your audience is your TA, so someone with a scientific background. Try to avoid being too casual, and don’t use phrases such as “I think” or “I wanted to know”. This doesn’t mean filling you page with scientific jargon and terminology.At the end of this module is an example of a properly written summary which you can use as an example.
FormatOne paragraphFont: Times New Roman, Size 12Standard (1″) page margins, single spaced.At the top of your page, include a header with the following information:A creative title related to the application/use of modern biotechnologyYour nameYour NSIDReferencesYour paragraph must include at least one in text citation from a peer-reviewed scientific journal. This means that you write, in your own words, what was found in the journal article, followed by the last name of the author(s) and the year the article was published in parenthesis.In scientific writing, you should not directly quote or use block quotations:It was found that “beta-carotene derived from golden rice is effectively converted to vitamin A in humans” (Tang et al 2009).Instead, you summarize in your own words:Golden rice can be used as a source of dietary Vitamin A (Tang et al 2009).Reference StyleWe will be using CSE Style (name-year system) for the format of citations and references.For in text citations, use the format (last name date). Examples:For a work with a single author, use (Wilson 1975).For a work with two authors, use (Anderson and May 1978).For more than two authors, cite the first author’s name and add et al. after: (Addy et al. 1998).The journal article you reference should be listed under the heading “Literature Cited”, using the format below. If you have more than one article referenced (which you shouldn’t; there’s no bonus for extra references), list them alphabetically by the last name of the first author.For your literature cited, use the format: Author(s). Date. Title of article. Abbreviated name of journal. Journal #: page numbers of entire article.Example:Addy HD, Boswell EP, and Koide RT. 1998. Low temperature acclimation and freezing resistance of extraradical VA mycorrhizal hyphae. Mycol. Res. 102: 582–586.
So all I have to do is list the articles?Not quite- there is one last thing that we are asking for to help streamline the marking process. You must include a PDF copy of every article that you reference (a link will not be accepted). All scientific journals give the option to download a PDF, assuming that you have access to the journal; it is typically a button labelled “PDF” at the top or side of the page. Alternatively, you can click on “Print” in your web browser, and select “Print to PDF” from the Printer options, which will allow you to save the entire webpage as a PDF to your local computer.As a U of S student, you will have automatic access to many journals (but not all). To access these from off campus, see the instructions given hereLinks to an external site..Note: If you do not have access to the full article, you should not be using it as a reference. This would be like reading the title of a Reddit or Facebook post and telling all of your friends about it, without ever reading the linked page itself; at best, you look foolish, at worst, you’re spreading misinformation that could hurt someone.
How to find a Peer-Reviewed Journal ArticleThere are several ways that you can find a reference with information on your topic. The Biology 301 Research GuideLinks to an external site. is a good place to start, and below are a couple of specific search engines designed for finding scientific articles. You can also use the references at the bottom of a Wikipedia page, as long as they point to a scientific article (and as long as you read the article; do not blindly believe that the Wikipedia author used the correct reference).1. Google Scholar (Links to an external site.)2. Web of ScienceLinks to an external site.
The RubricNow that you have an idea of what you need to do for this summary, you may be wondering how it will be marked. Due to the large number of students in this course, your TA’s will be using a rubric. The rubric can be found at the bottom of the Assignment Page (at the end of this module), but the categories are outlined below.Rubric CategoriesApplication Checked (1 mark): Did you send your application to your TA before the deadline?Format (1 mark): Did you use the correct font, include a header, and follow the other formatting instructions?Writing Quality (1 mark): Did you use correct grammar, sentence structure, and is everything spelled correctly? (i.e. can we understand what you wrote?)Application Validity (1 mark): Is your topic an actual use of biotechnology? (This should be a freebie if you got your application checked and gave your TA enough information).Description of Application (1 mark): Did you describe the application so that we know what it is (i.e. what the end product is)?Description of Benefit/Use (1 mark): Did you describe why this application is useful (i.e. why do we care)?Description of Biotechnology (1 mark): Did you describe the specific biotechnology used to produce the application? This includes genes manipulated, proteins produced, and any other necessary information. You do need some detail here.In Text Citation (1 mark): Did you include at least one in text citation, and did you follow the CSE style format given?Literature Cited (1 mark): Did you include at least one reference to a scientific, peer reviewed journal article, and did you list it following the CSE style format given?Article PDF Submitted (1 mark): Did you submit a PDF copy of all of the articles you listed in your literature cited? Links do not count for this mark.